General Information of the Compound
Compound ID
CP0487457
Compound Name
1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-ethyl}-3-(4-piperidin-1-yl-phenyl)-thiourea
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Structure
Formula
C26H28BrCl2N5S
Molecular Weight
593.422
Canonical SMILES
Clc1ccc(CN(CCNC(=S)Nc2ccc(cc2)N2CCCCC2)c2ccc(Br)cn2)cc1Cl
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InChI
InChI=1S/C26H28BrCl2N5S/c27-20-5-11-25(31-17-20)34(18-19-4-10-23(28)24(29)16-19)15-12-30-26(35)32-21-6-8-22(9-7-21)33-13-2-1-3-14-33/h4-11,16-17H,1-3,12-15,18H2,(H2,30,32,35)
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InChIKey
LOZIGROCVQDSGY-UHFFFAOYSA-N
Physicochemical Property
logP
7.1344
Rotatable Bonds
8
Heavy Atom Count
35
Polar Areas
43.43
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10698706
SID: 15732683
ChEMBL ID
CHEMBL142293
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01398, Somatostatin receptor type 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21 Mesocricetus auratus (Golden hamster)  1
1
Ki = 15000 nM
   TI
   LI
   LO
   TS