General Information of the Compound
Compound ID
CP0486541
Compound Name
N-(4-pyridin-2-ylphenyl)-4-(trifluoromethyl)benzamide
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Structure
Formula
C19H13F3N2O
Molecular Weight
342.32
Canonical SMILES
FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccccn1
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InChI
InChI=1S/C19H13F3N2O/c20-19(21,22)15-8-4-14(5-9-15)18(25)24-16-10-6-13(7-11-16)17-3-1-2-12-23-17/h1-12H,(H,24,25)
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InChIKey
KQIDEDJHNOBDNP-UHFFFAOYSA-N
Physicochemical Property
logP
5.0197
Rotatable Bonds
3
Heavy Atom Count
25
Polar Areas
41.99
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44412456
ChEMBL ID
CHEMBL209112
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1500 nM
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