General Information of the Compound
Compound ID
CP0486103
Compound Name
9(10H)-anthracenone
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Synonyms
10-hydroanthracen-9-one
10H-anthracen-9-one
9(10H)-Anthracenone
9,10-Dihydro-9-ketoanthracene
9,10-Dihydro-9-oxoanthracene
9-10-dihydro-9-oxoanthracene
9-Oxoanthracene
9-anthrone
90-44-8
A-8100
AC1L1NTG
AI3-11256
ANTHRONE
Anthracene, 9,10-dihydro-9-oxo-
Anthranone
Anthrone, 95%, pure
Anthrone, 96%
Anthrone, ACS reagent
Az-O
CCRIS 3175
CHEBI:33835
CHEMBL124440
Carbothrone
EINECS 201-994-0
FP0FJ7K744
HSDB 2158
MFCD00001187
NSC 1965
RJGDLRCDCYRQOQ-UHFFFAOYSA-N
UNII-FP0FJ7K744
anthracen-9(10H)-one
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Structure
Formula
C14H10O
Molecular Weight
194.233
Canonical SMILES
O=C1c2ccccc2Cc2ccccc12
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InChI
InChI=1S/C14H10O/c15-14-12-7-3-1-5-10(12)9-11-6-2-4-8-13(11)14/h1-8H,9H2
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InChIKey
RJGDLRCDCYRQOQ-UHFFFAOYSA-N
CAS
90-44-8
Physicochemical Property
logP
2.8218
Rotatable Bonds
0
Heavy Atom Count
15
Polar Areas
17.07
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Complexity
15

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 7018
SID: 14748588
ChEMBL ID
CHEMBL124440
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00205, 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000150 HaCaT Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( ANTHRONE )
Drug Name ANTHRONE
Target(s)
Arachidonate 5-lipoxygenase (5-LOX)
Inhibitor