General Information of the Compound
Compound ID
CP0485743
Compound Name
3-[2-[(4-bromophenyl)methyl]benzimidazol-1-yl]-N,N-dimethylpropan-1-amine
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Structure
Formula
C19H22BrN3
Molecular Weight
372.31
Canonical SMILES
CN(C)CCCn1c(Cc2ccc(Br)cc2)nc2ccccc12
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InChI
InChI=1S/C19H22BrN3/c1-22(2)12-5-13-23-18-7-4-3-6-17(18)21-19(23)14-15-8-10-16(20)11-9-15/h3-4,6-11H,5,12-14H2,1-2H3
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InChIKey
WNONMKHHEOLVQW-UHFFFAOYSA-N
Physicochemical Property
logP
4.3413
Rotatable Bonds
6
Heavy Atom Count
23
Polar Areas
21.06
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44456855
ChEMBL ID
CHEMBL272631
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
EC50 = 2600 nM
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