General Information of the Compound
Compound ID
CP0485183
Compound Name
N-[3-[[2-oxo-3-(phenylcarbamoylamino)-4,5-dihydro-3H-1-benzazepin-1-yl]methyl]phenyl]morpholine-4-carboxamide
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Structure
Formula
C29H31N5O4
Molecular Weight
513.598
Canonical SMILES
O=C(NC1CCc2ccccc2N(Cc2cccc(NC(=O)N3CCOCC3)c2)C1=O)Nc1ccccc1
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InChI
InChI=1S/C29H31N5O4/c35-27-25(32-28(36)30-23-9-2-1-3-10-23)14-13-22-8-4-5-12-26(22)34(27)20-21-7-6-11-24(19-21)31-29(37)33-15-17-38-18-16-33/h1-12,19,25H,13-18,20H2,(H,31,37)(H2,30,32,36)
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InChIKey
NCBJSPJNKCAVLT-UHFFFAOYSA-N
Physicochemical Property
logP
4.2204
Rotatable Bonds
5
Heavy Atom Count
38
Polar Areas
103.01
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10839510
SID: 15880960
ChEMBL ID
CHEMBL312997
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS