General Information of the Compound
| Compound ID |
CP0484422
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| Compound Name |
1-N'-[3-fluoro-4-(6-hydroxy-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl)oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
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| Structure |
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| Formula |
C24H19F2N5O4
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| Molecular Weight |
479.443
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| Canonical SMILES |
Cc1c(O)cn2ncnc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12
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| InChI |
InChI=1S/C24H19F2N5O4/c1-13-18(32)11-31-20(13)21(27-12-28-31)35-19-7-6-16(10-17(19)26)30-23(34)24(8-9-24)22(33)29-15-4-2-14(25)3-5-15/h2-7,10-12,32H,8-9H2,1H3,(H,29,33)(H,30,34)
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| InChIKey |
LCBHERHFOXMRNB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound