General Information of the Compound
| Compound ID |
CP0484421
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| Compound Name |
1-N'-[4-(6-ethoxy-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl)oxy-3-fluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
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| Structure |
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| Formula |
C26H23F2N5O4
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| Molecular Weight |
507.497
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| Canonical SMILES |
CCOc1cn2ncnc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c2c1C
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| InChI |
InChI=1S/C26H23F2N5O4/c1-3-36-21-13-33-22(15(21)2)23(29-14-30-33)37-20-9-8-18(12-19(20)28)32-25(35)26(10-11-26)24(34)31-17-6-4-16(27)5-7-17/h4-9,12-14H,3,10-11H2,1-2H3,(H,31,34)(H,32,35)
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| InChIKey |
OMKHRIXSTDJJIS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound