General Information of the Compound
| Compound ID |
CP0484279
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| Compound Name |
4-chloro-N-[2-methoxy-5-(4-oxopyrido[1,2-a]pyrimidin-7-yl)pyridin-3-yl]benzenesulfonamide
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| Structure |
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| Formula |
C20H15ClN4O4S
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| Molecular Weight |
442.884
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| Canonical SMILES |
COc1ncc(cc1NS(=O)(=O)c1ccc(Cl)cc1)-c1ccc2nccc(=O)n2c1
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| InChI |
InChI=1S/C20H15ClN4O4S/c1-29-20-17(24-30(27,28)16-5-3-15(21)4-6-16)10-14(11-23-20)13-2-7-18-22-9-8-19(26)25(18)12-13/h2-12,24H,1H3
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| InChIKey |
WMMJZVSXILOMRC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01065, Serine/threonine-protein kinase mTOR