General Information of the Compound
| Compound ID |
CP0483759
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
6-[[acetyl(propan-2-yl)amino]methyl]-N-(5-cyano-4-propan-2-yloxypyridin-2-yl)-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C25H30N6O4
|
||||||||||||||||||
| Molecular Weight |
478.553
|
||||||||||||||||||
| Canonical SMILES |
CC(C)Oc1cc(NC(=O)N2CCCc3cc(CN(C(C)C)C(C)=O)c(C=O)nc23)ncc1C#N
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C25H30N6O4/c1-15(2)31(17(5)33)13-19-9-18-7-6-8-30(24(18)28-21(19)14-32)25(34)29-23-10-22(35-16(3)4)20(11-26)12-27-23/h9-10,12,14-16H,6-8,13H2,1-5H3,(H,27,29,34)
Show/Hide
|
||||||||||||||||||
| InChIKey |
ONOWRSVLYIIVOM-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4