General Information of the Compound
| Compound ID |
CP0483636
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| Compound Name |
8-isoquinolin-7-yl-4-methyl-2-phenylpyrazolo[1,5-a]quinazolin-5-one
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| Structure |
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| Formula |
C26H18N4O
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| Molecular Weight |
402.457
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| Canonical SMILES |
Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2ccncc2c1)-c1ccccc1
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| InChI |
InChI=1S/C26H18N4O/c1-29-25-15-23(18-5-3-2-4-6-18)28-30(25)24-14-20(9-10-22(24)26(29)31)19-8-7-17-11-12-27-16-21(17)13-19/h2-16H,1H3
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| InChIKey |
DUOKBXVNMNQTRT-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01491, Metabotropic glutamate receptor 2
Protein ID: PT03263, Metabotropic glutamate receptor 3