General Information of the Compound
| Compound ID |
CP0480273
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| Compound Name |
N-[[3-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-6-yl]methyl]-N-methyl-5-[2-methyl-4-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1,3,4-oxadiazol-2-amine
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| Formula |
C31H36N10O
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| Molecular Weight |
564.698
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| Canonical SMILES |
CN(C)CCn1cc(cn1)-c1cnc2ccc(CN(C)c3nnc(o3)-c3ccc(cc3C)-c3c(C)nn(C)c3C)cn12
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| InChI |
InChI=1S/C31H36N10O/c1-20-14-24(29-21(2)36-39(7)22(29)3)9-10-26(20)30-34-35-31(42-30)38(6)17-23-8-11-28-32-16-27(41(28)18-23)25-15-33-40(19-25)13-12-37(4)5/h8-11,14-16,18-19H,12-13,17H2,1-7H3
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| InChIKey |
OMAJOUIXIRWQLC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT01661, Tyrosine-protein kinase receptor TYRO3
Protein ID: PT01128, Tyrosine-protein kinase receptor UFO