General Information of the Compound
Compound ID
CP0479990
Compound Name
butyl N-[3-[3-[2-(2-ethylimidazol-1-yl)acetyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate
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Structure
Formula
C26H33N3O5S2
Molecular Weight
531.7
Canonical SMILES
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1cccc(c1)C(=O)Cn1ccnc1CC
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InChI
InChI=1S/C26H33N3O5S2/c1-5-7-13-34-26(31)28-36(32,33)25-22(16-21(35-25)14-18(3)4)19-9-8-10-20(15-19)23(30)17-29-12-11-27-24(29)6-2/h8-12,15-16,18H,5-7,13-14,17H2,1-4H3,(H,28,31)
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InChIKey
OTPYHEJTUKIBIA-UHFFFAOYSA-N
Physicochemical Property
logP
5.4704
Rotatable Bonds
12
Heavy Atom Count
36
Polar Areas
107.36
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 67133138
ChEMBL ID
CHEMBL2086911
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01553, Type-2 angiotensin II receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 48 nM
   TI
   LI
   LO
   TS