General Information of the Compound
Compound ID
CP0478453
Compound Name
1'-[5-[(2R)-1-benzylpyrrolidin-2-yl]pent-4-enyl]spiro[1,2-dihydroisoindole-3,4'-piperidine]
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Structure
Formula
C28H37N3
Molecular Weight
415.625
Canonical SMILES
C(CC=C[C@H]1CCCN1Cc1ccccc1)CN1CCC2(CC1)NCc1ccccc21
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InChI
InChI=1S/C28H37N3/c1-3-10-24(11-4-1)23-31-19-9-14-26(31)13-5-2-8-18-30-20-16-28(17-21-30)27-15-7-6-12-25(27)22-29-28/h1,3-7,10-13,15,26,29H,2,8-9,14,16-23H2/t26-/m0/s1
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InChIKey
LSDFJSYOCQOIOD-SANMLTNESA-N
Physicochemical Property
logP
5.0819
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
18.51
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57391870
ChEMBL ID
CHEMBL1783824
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS