General Information of the Compound
Compound ID
CP0476205
Compound Name
1-(3-acetyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)-4-[4-(3-methylphenyl)piperidin-1-yl]butan-1-one
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Structure
Formula
C28H36N2O2
Molecular Weight
432.608
Canonical SMILES
CC(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1cccc(C)c1
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InChI
InChI=1S/C28H36N2O2/c1-21-5-3-6-25(19-21)24-10-15-29(16-11-24)14-4-7-28(32)27-9-8-23-12-17-30(22(2)31)18-13-26(23)20-27/h3,5-6,8-9,19-20,24H,4,7,10-18H2,1-2H3
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InChIKey
XUVBZWZGJVYTGN-UHFFFAOYSA-N
Physicochemical Property
logP
4.78462
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
40.62
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57396293
ChEMBL ID
CHEMBL1914626
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1200 nM
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