General Information of the Compound
Compound ID
CP0475429
Compound Name
3-(2,5-dimethylphenylsulfonyl)-5-(4-methylpiperidin-1-yl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine
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Structure
Formula
C21H23N5O2S2
Molecular Weight
441.582
Canonical SMILES
CC1CCN(CC1)c1nc2c(nnn2c2ccsc12)S(=O)(=O)c1cc(C)ccc1C
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InChI
InChI=1S/C21H23N5O2S2/c1-13-6-9-25(10-7-13)19-18-16(8-11-29-18)26-20(22-19)21(23-24-26)30(27,28)17-12-14(2)4-5-15(17)3/h4-5,8,11-13H,6-7,9-10H2,1-3H3
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InChIKey
LSABJHJMQVOZLB-UHFFFAOYSA-N
Physicochemical Property
logP
4.02494
Rotatable Bonds
3
Heavy Atom Count
30
Polar Areas
80.46
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49799663
ChEMBL ID
CHEMBL1170664
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1990 nM
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