General Information of the Compound
Compound ID
CP0472258
Compound Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-aminopent-4-enoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]pent-4-enoyl]amino]-4-methylpentanoic acid
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Structure
Formula
C36H55N7O8
Molecular Weight
713.877
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=C)C(O)=O
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InChI
InChI=1S/C36H55N7O8/c1-5-10-25(38)31(45)40-27(12-7-8-18-37)35(49)43-19-9-13-30(43)34(48)41-28(21-23-14-16-24(44)17-15-23)33(47)39-26(11-6-2)32(46)42-29(36(50)51)20-22(3)4/h5-6,14-17,22,25-30,44H,1-2,7-13,18-21,37-38H2,3-4H3,(H,39,47)(H,40,45)(H,41,48)(H,42,46)(H,50,51)/t25-,26-,27-,28-,29-,30-/m0/s1
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InChIKey
WNEPMRPWKIJRLO-WPMUBMLPSA-N
Physicochemical Property
logP
0.6041
Rotatable Bonds
22
Heavy Atom Count
51
Polar Areas
246.28
Hydrogen Bond Donor Count
8
Hydrogen Bond Acceptor Count
9
Complexity
51

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145979804
ChEMBL ID
CHEMBL4283301
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02429, Neurotensin receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1700 nM
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