General Information of the Compound
Compound ID
CP0471377
Compound Name
1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-[(5-oxo-1,4-dihydro-1,2,4-triazol-3-yl)methyl]benzimidazol-2-one
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Structure
Formula
C29H38N6O4
Molecular Weight
534.661
Canonical SMILES
COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(Cc3n[nH]c(=O)[nH]3)c2=O)C(C)C)c1
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InChI
InChI=1S/C29H38N6O4/c1-19(2)25(39-26-17-22(38-4)10-9-20(26)3)13-16-33-14-11-21(12-15-33)35-24-8-6-5-7-23(24)34(29(35)37)18-27-30-28(36)32-31-27/h5-10,17,19,21,25H,11-16,18H2,1-4H3,(H2,30,31,32,36)
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InChIKey
ZSBHXKLQJNQJOJ-UHFFFAOYSA-N
Physicochemical Property
logP
3.71032
Rotatable Bonds
10
Heavy Atom Count
39
Polar Areas
110.17
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 136036819
ChEMBL ID
CHEMBL259291
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 25.12 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.888 nM
   TI
   LI
   LO
   TS