General Information of the Compound
Compound ID
CP0471142
Compound Name
5,7-dichloro-3-(4-hydroxy-3-nitrophenyl)-3-methylquinoline-2,4(1H,3H)-dione
    Show/Hide
Structure
Formula
C16H10Cl2N2O5
Molecular Weight
381.171
Canonical SMILES
CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(O)c(c1)[N+]([O-])=O
    Show/Hide
InChI
InChI=1S/C16H10Cl2N2O5/c1-16(7-2-3-12(21)11(4-7)20(24)25)14(22)13-9(18)5-8(17)6-10(13)19-15(16)23/h2-6,21H,1H3,(H,19,23)
    Show/Hide
InChIKey
DKLDLVBOAWNIDS-UHFFFAOYSA-N
Physicochemical Property
logP
3.6999
Rotatable Bonds
2
Heavy Atom Count
25
Polar Areas
109.54
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 11653799
SID: 16757320
ChEMBL ID
CHEMBL253513
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS