General Information of the Compound
Compound ID
CP0469306
Compound Name
(2R)-5-[[amino-[[1-(4-azidophenyl)triazol-4-yl]methylcarbamoylamino]methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamide
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Structure
Formula
C37H38N12O4
Molecular Weight
714.791
Canonical SMILES
N\C(NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1)=N\C(=O)NCc1cn(nn1)-c1ccc(cc1)N=[N+]=[N-]
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InChI
InChI=1S/C37H38N12O4/c38-36(44-37(53)42-23-29-24-49(48-46-29)30-17-15-28(16-18-30)45-47-39)40-21-7-12-32(34(51)41-22-25-13-19-31(50)20-14-25)43-35(52)33(26-8-3-1-4-9-26)27-10-5-2-6-11-27/h1-6,8-11,13-20,24,32-33,50H,7,12,21-23H2,(H,41,51)(H,43,52)(H4,38,40,42,44,53)/t32-/m1/s1
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InChIKey
WAOGXRNMPWEBGZ-JGCGQSQUSA-N
Physicochemical Property
logP
4.4421
Rotatable Bonds
15
Heavy Atom Count
53
Polar Areas
237.41
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
8
Complexity
53

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127041307
ChEMBL ID
CHEMBL3746796
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 4.5 nM
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   LI
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