General Information of the Compound
| Compound ID |
CP0466815
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| Compound Name |
4-methoxy-N-[2-methoxy-5-(4-oxopyrido[1,2-a]pyrimidin-7-yl)pyridin-3-yl]benzenesulfonamide
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| Structure |
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| Formula |
C21H18N4O5S
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| Molecular Weight |
438.465
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| Canonical SMILES |
COc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nccc(=O)n2c1
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| InChI |
InChI=1S/C21H18N4O5S/c1-29-16-4-6-17(7-5-16)31(27,28)24-18-11-15(12-23-21(18)30-2)14-3-8-19-22-10-9-20(26)25(19)13-14/h3-13,24H,1-2H3
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| InChIKey |
HWMJJIJRAKNKJM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01065, Serine/threonine-protein kinase mTOR