General Information of the Compound
Compound ID
CP0462347
Compound Name
6-[4-(1-methylpropyl)phenyl]-3-[2-(4-morpholinylmethyl)-6-quinolinyl]thieno[3,2-d]pyrimidin-4(3H)-one
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Structure
Formula
C30H30N4O2S
Molecular Weight
510.663
Canonical SMILES
CCC(C)c1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCOCC5)ccc4c3)c(=O)c2s1
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InChI
InChI=1S/C30H30N4O2S/c1-3-20(2)21-4-6-22(7-5-21)28-17-27-29(37-28)30(35)34(19-31-27)25-10-11-26-23(16-25)8-9-24(32-26)18-33-12-14-36-15-13-33/h4-11,16-17,19-20H,3,12-15,18H2,1-2H3
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InChIKey
DVZUMXKYIYIBCL-UHFFFAOYSA-N
Physicochemical Property
logP
6.0081
Rotatable Bonds
6
Heavy Atom Count
37
Polar Areas
60.25
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11995141
SID: 17494258
ChEMBL ID
CHEMBL215782
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 200 nM
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