General Information of the Compound
Compound ID
CP0461878
Compound Name
7-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octahydro-indolizin-7-ol
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Structure
Formula
C26H26N2O3S
Molecular Weight
446.572
Canonical SMILES
OC1(CCN2CCCC2C1)c1ccc2ccn(c2c1)S(=O)(=O)c1cccc2ccccc12
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InChI
InChI=1S/C26H26N2O3S/c29-26(13-16-27-14-4-7-22(27)18-26)21-11-10-20-12-15-28(24(20)17-21)32(30,31)25-9-3-6-19-5-1-2-8-23(19)25/h1-3,5-6,8-12,15,17,22,29H,4,7,13-14,16,18H2
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InChIKey
WHASPDDANATWBF-UHFFFAOYSA-N
Physicochemical Property
logP
4.4773
Rotatable Bonds
3
Heavy Atom Count
32
Polar Areas
62.54
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44292800
ChEMBL ID
CHEMBL45987
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4.7 nM
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