General Information of the Compound
| Compound ID |
CP0461231
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| Compound Name |
4-fluoro-N-(4-(6-(isopropyl(methyl)amino)pyrimidin-4-yl)thiazol-2-yl)-N-methylbenzamide
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| Structure |
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| Formula |
C19H20FN5OS
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| Molecular Weight |
385.468
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| Canonical SMILES |
CC(C)N(C)c1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(F)cc1
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| InChI |
InChI=1S/C19H20FN5OS/c1-12(2)24(3)17-9-15(21-11-22-17)16-10-27-19(23-16)25(4)18(26)13-5-7-14(20)8-6-13/h5-12H,1-4H3
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| InChIKey |
QUUDJJDYMOHMGD-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01994, Metabotropic glutamate receptor 1
Protein ID: PT00854, Metabotropic glutamate receptor 5