General Information of the Compound
| Compound ID |
CP0461085
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| Compound Name |
4-(2-hydroxyethyl)-2-phenyl-8-pyridin-3-ylpyrazolo[1,5-a]quinazolin-5-one
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| Structure |
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| Formula |
C23H18N4O2
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| Molecular Weight |
382.423
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| Canonical SMILES |
OCCn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1
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| InChI |
InChI=1S/C23H18N4O2/c28-12-11-26-22-14-20(16-5-2-1-3-6-16)25-27(22)21-13-17(8-9-19(21)23(26)29)18-7-4-10-24-15-18/h1-10,13-15,28H,11-12H2
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| InChIKey |
KSNWGOKZUICFQD-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01491, Metabotropic glutamate receptor 2
Protein ID: PT03263, Metabotropic glutamate receptor 3