General Information of the Compound
Compound ID
CP0460878
Compound Name
(2R)-6-amino-2-[[2-[3-[(2S)-1-amino-1-oxo-3-(4-phenylphenyl)propan-2-yl]-4-oxo-2-phenyl-1,3-thiazolidin-5-yl]acetyl]amino]hexanamide
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Structure
Formula
C32H37N5O4S
Molecular Weight
587.746
Canonical SMILES
NCCCC[C@@H](NC(=O)CC1SC(N([C@@H](Cc2ccc(cc2)-c2ccccc2)C(N)=O)C1=O)c1ccccc1)C(N)=O
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InChI
InChI=1S/C32H37N5O4S/c33-18-8-7-13-25(29(34)39)36-28(38)20-27-31(41)37(32(42-27)24-11-5-2-6-12-24)26(30(35)40)19-21-14-16-23(17-15-21)22-9-3-1-4-10-22/h1-6,9-12,14-17,25-27,32H,7-8,13,18-20,33H2,(H2,34,39)(H2,35,40)(H,36,38)/t25-,26+,27?,32?/m1/s1
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InChIKey
KRUHAHDGPMQZAF-TYJZTFFYSA-N
Physicochemical Property
logP
2.882
Rotatable Bonds
14
Heavy Atom Count
42
Polar Areas
161.61
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44345981
ChEMBL ID
CHEMBL120607
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01196, Somatostatin receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1412.54 nM
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