General Information of the Compound
Compound ID
CP0460434
Compound Name
(3-phenylphenyl) 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
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Structure
Formula
C20H22N2O2
Molecular Weight
322.408
Canonical SMILES
O=C(Oc1cccc(c1)-c1ccccc1)N1CCN2CCC1CC2
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InChI
InChI=1S/C20H22N2O2/c23-20(22-14-13-21-11-9-18(22)10-12-21)24-19-8-4-7-17(15-19)16-5-2-1-3-6-16/h1-8,15,18H,9-14H2
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InChIKey
AVUBBCJSYRFMJV-UHFFFAOYSA-N
Physicochemical Property
logP
3.6324
Rotatable Bonds
2
Heavy Atom Count
24
Polar Areas
32.78
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45270095
ChEMBL ID
CHEMBL552005
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
Ki = 9 nM
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