General Information of the Compound
Compound ID
CP0460171
Compound Name
2-(6-methoxy-3-oxo-1,2-dihydroinden-2-yl)-N-(3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropyl)acetamide
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Structure
Formula
C28H34N2O3
Molecular Weight
446.591
Canonical SMILES
COc1ccc2C(=O)C(CC(=O)NCCCN3CCC4(CCc5ccccc45)CC3)Cc2c1
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InChI
InChI=1S/C28H34N2O3/c1-33-23-7-8-24-21(18-23)17-22(27(24)32)19-26(31)29-13-4-14-30-15-11-28(12-16-30)10-9-20-5-2-3-6-25(20)28/h2-3,5-8,18,22H,4,9-17,19H2,1H3,(H,29,31)
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InChIKey
GPKMACNWBYWTPW-UHFFFAOYSA-N
Physicochemical Property
logP
3.9266
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
58.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44407078
ChEMBL ID
CHEMBL381240
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
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