General Information of the Compound
Compound ID
CP0456601
Compound Name
3-[[1-(4-methoxyphenyl)ethyl-(quinoline-3-carbonyl)amino]methyl]benzoic acid
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Structure
Formula
C27H24N2O4
Molecular Weight
440.499
Canonical SMILES
COc1ccc(cc1)C(C)N(Cc1cccc(c1)C(O)=O)C(=O)c1cnc2ccccc2c1
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InChI
InChI=1S/C27H24N2O4/c1-18(20-10-12-24(33-2)13-11-20)29(17-19-6-5-8-22(14-19)27(31)32)26(30)23-15-21-7-3-4-9-25(21)28-16-23/h3-16,18H,17H2,1-2H3,(H,31,32)
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InChIKey
CISIDUHYOJBXAM-UHFFFAOYSA-N
Physicochemical Property
logP
5.3452
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
79.73
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 122178106
ChEMBL ID
CHEMBL3577901
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03065, Transient receptor potential cation channel subfamily M member 8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6104 nM
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