General Information of the Compound
Compound ID
CP0456465
Compound Name
(2S,3S,4R,5R)-3,4-dihydroxy-5-[6-[(2-methoxyphenyl)methylamino]purin-9-yl]-N-methylselenolane-2-carboxamide
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Structure
Formula
C19H22N6O4Se
Molecular Weight
477.383
Canonical SMILES
CNC(=O)[C@H]1[Se][C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccccc3OC)ncnc12
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InChI
InChI=1S/C19H22N6O4Se/c1-20-18(28)15-13(26)14(27)19(30-15)25-9-24-12-16(22-8-23-17(12)25)21-7-10-5-3-4-6-11(10)29-2/h3-6,8-9,13-15,19,26-27H,7H2,1-2H3,(H,20,28)(H,21,22,23)/t13-,14+,15-,19+/m0/s1
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InChIKey
DMJZERIZAOVMHE-QCUYGVNKSA-N
Physicochemical Property
logP
-0.0803
Rotatable Bonds
6
Heavy Atom Count
30
Polar Areas
134.42
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
9
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137636769
ChEMBL ID
CHEMBL4059807
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00840, Adenosine receptor A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1880 nM
   TI
   LI
   LO
   TS
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1260 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.75 nM
   TI
   LI
   LO
   TS