General Information of the Compound
| Compound ID |
CP0456199
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| Compound Name |
N-hydroxy-4-[[7-methoxy-2,4-dioxo-3-(2-phenylethyl)quinazolin-1-yl]methyl]benzamide
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| Structure |
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| Formula |
C25H23N3O5
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| Molecular Weight |
445.475
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| Canonical SMILES |
COc1ccc2c(c1)n(Cc1ccc(cc1)C(=O)NO)c(=O)n(CCc1ccccc1)c2=O
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| InChI |
InChI=1S/C25H23N3O5/c1-33-20-11-12-21-22(15-20)28(16-18-7-9-19(10-8-18)23(29)26-32)25(31)27(24(21)30)14-13-17-5-3-2-4-6-17/h2-12,15,32H,13-14,16H2,1H3,(H,26,29)
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| InChIKey |
SQBBNABXOTUYRL-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8