General Information of the Compound
Compound ID
CP0455630
Compound Name
N,N'-bis[2-(5-methoxy-1H-indol-3-yl)ethyl]decanediamide
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Structure
Formula
C32H42N4O4
Molecular Weight
546.712
Canonical SMILES
COc1ccc2[nH]cc(CCNC(=O)CCCCCCCCC(=O)NCCc3c[nH]c4ccc(OC)cc34)c2c1
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InChI
InChI=1S/C32H42N4O4/c1-39-25-11-13-29-27(19-25)23(21-35-29)15-17-33-31(37)9-7-5-3-4-6-8-10-32(38)34-18-16-24-22-36-30-14-12-26(40-2)20-28(24)30/h11-14,19-22,35-36H,3-10,15-18H2,1-2H3,(H,33,37)(H,34,38)
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InChIKey
KZBZGFPPEMRULN-UHFFFAOYSA-N
Physicochemical Property
logP
5.8048
Rotatable Bonds
17
Heavy Atom Count
40
Polar Areas
108.24
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44424026
ChEMBL ID
CHEMBL388591
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01843, Melatonin receptor type 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 387 nM
   TI
   LI
   LO
   TS
Protein ID: PT02174, Melatonin receptor type 1B
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 573 nM
   TI
   LI
   LO
   TS