General Information of the Compound
Compound ID
CP0454612
Compound Name
US9469631, 22
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Structure
Formula
C21H30N6O3
Molecular Weight
414.51
Canonical SMILES
CC(C)(C)OC(=O)N1CCC(CC1)N(C1CC1)C(=O)c1ccc(cc1)N1NNN=C1
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InChI
InChI=1S/C21H30N6O3/c1-21(2,3)30-20(29)25-12-10-18(11-13-25)27(17-8-9-17)19(28)15-4-6-16(7-5-15)26-14-22-23-24-26/h4-7,14,17-18,23-24H,8-13H2,1-3H3
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InChIKey
VWADGCHLXPIJKV-UHFFFAOYSA-N
Physicochemical Property
logP
2.4632
Rotatable Bonds
4
Heavy Atom Count
30
Polar Areas
89.51
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 89995549
ChEMBL ID
CHEMBL3939288
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000613 MIN6 Mus musculus (Mouse)  1
1
EC50 = 137 nM
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