General Information of the Compound
Compound ID
CP0454320
Compound Name
N-cyclohexyl-7-methoxy-1-(2-morpholin-4-ylethyl)-4-oxoquinoline-3-carboxamide
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Structure
Formula
C23H31N3O4
Molecular Weight
413.518
Canonical SMILES
COc1ccc2c(c1)n(CCN1CCOCC1)cc(C(=O)NC1CCCCC1)c2=O
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InChI
InChI=1S/C23H31N3O4/c1-29-18-7-8-19-21(15-18)26(10-9-25-11-13-30-14-12-25)16-20(22(19)27)23(28)24-17-5-3-2-4-6-17/h7-8,15-17H,2-6,9-14H2,1H3,(H,24,28)
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InChIKey
TXZJFGWULOAGLG-UHFFFAOYSA-N
Physicochemical Property
logP
2.4048
Rotatable Bonds
6
Heavy Atom Count
30
Polar Areas
72.8
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44444733
ChEMBL ID
CHEMBL398446
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2920 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 79 nM
   TI
   LI
   LO
   TS