General Information of the Compound
Compound ID
CP0453509
Compound Name
N-hydroxy-N-methylbenzamide
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Synonyms
2446-50-6
AC1L83FX
AC1Q5INQ
AKOS028111405
BDBM50015122
CHEMBL101043
CTK0J4869
DDSSLJHUWRMSSP-UHFFFAOYSA-N
DTXSID20327327
N-Hydroxy-N-methyl-benzamide
N-Hydroxy-N-methylbenzamide
N-Methyl-N-hydroxybenzamide
N-benzoyl-N-methylhydroxylamine
NSC-646164
NSC646164
SCHEMBL125680
ZINC5497333
benzamide, N-hydroxy-N-methyl-
n-methylbenzohydroxamic acid
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Structure
Formula
C8H9NO2
Molecular Weight
151.165
Canonical SMILES
CN(O)C(=O)c1ccccc1
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InChI
InChI=1S/C8H9NO2/c1-9(11)8(10)7-5-3-2-4-6-7/h2-6,11H,1H3
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InChIKey
DDSSLJHUWRMSSP-UHFFFAOYSA-N
Physicochemical Property
logP
1.1478
Rotatable Bonds
1
Heavy Atom Count
11
Polar Areas
40.54
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
11

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 371715
SID: 15412999
ChEMBL ID
CHEMBL101043
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01743, Polyunsaturated fatty acid 5-lipoxygenase
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000194 RBL-1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 14000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( N-Hydroxy-N-methyl-benzamide )
Drug Name N-Hydroxy-N-methyl-benzamide
Target(s)
Arachidonate 5-lipoxygenase (5-LOX)
 Target Info 
Inhibitor