General Information of the Compound
Compound ID
CP0449599
Compound Name
1-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-2-N-phenylcyclohexane-1,2-dicarboxamide
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Structure
Formula
C30H39N3O2
Molecular Weight
473.661
Canonical SMILES
O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1CCCCC1C(=O)Nc1ccccc1
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InChI
InChI=1S/C30H39N3O2/c34-28(25-12-5-6-13-26(25)29(35)32-24-10-2-1-3-11-24)31-19-8-20-33-21-17-30(18-22-33)16-15-23-9-4-7-14-27(23)30/h1-4,7,9-11,14,25-26H,5-6,8,12-13,15-22H2,(H,31,34)(H,32,35)
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InChIKey
QHFGJWHNWJVSNC-UHFFFAOYSA-N
Physicochemical Property
logP
4.9178
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
61.44
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44406979
ChEMBL ID
CHEMBL201916
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS