General Information of the Compound
Compound ID
CP0447417
Compound Name
2-(1-ethyl-5-methoxyindol-3-yl)-N,N-dimethylethanamine
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Structure
Formula
C15H22N2O
Molecular Weight
246.354
Canonical SMILES
CCn1cc(CCN(C)C)c2cc(OC)ccc12
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InChI
InChI=1S/C15H22N2O/c1-5-17-11-12(8-9-16(2)3)14-10-13(18-4)6-7-15(14)17/h6-7,10-11H,5,8-9H2,1-4H3
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InChIKey
NROYJCARPGQFQY-UHFFFAOYSA-N
Physicochemical Property
logP
2.7739
Rotatable Bonds
5
Heavy Atom Count
18
Polar Areas
17.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
18

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10800458
SID: 15839871
ChEMBL ID
CHEMBL7166
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 240 nM
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