General Information of the Compound
| Compound ID |
CP0447127
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| Compound Name |
3-[2-(4-fluorophenyl)-4-methyl-5-oxopyrazolo[1,5-a]quinazolin-8-yl]benzenesulfonamide
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| Structure |
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| Formula |
C23H17FN4O3S
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| Molecular Weight |
448.479
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| Canonical SMILES |
Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccc(F)cc1
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| InChI |
InChI=1S/C23H17FN4O3S/c1-27-22-13-20(14-5-8-17(24)9-6-14)26-28(22)21-12-16(7-10-19(21)23(27)29)15-3-2-4-18(11-15)32(25,30)31/h2-13H,1H3,(H2,25,30,31)
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| InChIKey |
UZYIZTJCLHAUKM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01491, Metabotropic glutamate receptor 2
Protein ID: PT03263, Metabotropic glutamate receptor 3