General Information of the Compound
| Compound ID |
CP0446809
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| Compound Name |
9-NC
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| Synonyms |
Inhaled Orathecin
(4s)-4-ethyl-4-hydroxy-10-nitro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
(S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(s)-4-ethyl-4-hydroxy-10-nitro-1h-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
9-NC
9-Nitro-20(S)-camptothecin
9-Nitrocamptothecin
9-Nitrocamptothecin (9-NC)
9-nitro-20(S)-camptothecin
91421-42-0
9NC
Aerosolized liposomal 9 nitro-20 (S) camptothecin
C20H15N3O6
CHEBI:90225
Camptogen
H19C446XXB
L9NC
NCGC00167969-01
Nitrocamptothecin
Orathecin
Q-100889
RFS 2000
RFS-2000
Rubitecan
Rubitecan (inhaled)
Rubitecan (inhaled), SuperGen
UNII-H19C446XXB
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| Structure |
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| Formula |
C20H15N3O6
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| Molecular Weight |
393.355
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| Canonical SMILES |
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc([N+]([O-])=O)c4cc3Cn1c2=O
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| InChI |
InChI=1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1
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| InChIKey |
VHXNKPBCCMUMSW-FQEVSTJZSA-N
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| CAS |
91421-42-0
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03217, ATP-binding cassette sub-family C member 2
Protein ID: PT03222, ATP-binding cassette sub-family C member 3
Protein ID: PT05334, ATP-binding cassette sub-family C member 4
Protein ID: PT06109, Geminin
Clinical Information about the Compound