General Information of the Compound
Compound ID
CP0445714
Compound Name
2-[5-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-1H-indol-3-yl]-N,N-dimethyl-2-oxo-acetamide
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Structure
Formula
C21H18ClN3O4S2
Molecular Weight
475.979
Canonical SMILES
CN(C)C(=O)C(=O)c1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12
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InChI
InChI=1S/C21H18ClN3O4S2/c1-11-14-8-12(22)4-7-18(14)30-21(11)31(28,29)24-13-5-6-17-15(9-13)16(10-23-17)19(26)20(27)25(2)3/h4-10,23-24H,1-3H3
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InChIKey
OPBCKFXRSPVNPI-UHFFFAOYSA-N
Physicochemical Property
logP
4.41612
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
99.34
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11190716
SID: 16271762
ChEMBL ID
CHEMBL367636
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS