General Information of the Compound
| Compound ID |
CP0445672
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| Compound Name |
N-[2-chloro-5-(4-oxopyrido[1,2-a]pyrimidin-7-yl)pyridin-3-yl]-2-fluorobenzenesulfonamide
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| Structure |
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| Formula |
C19H12ClFN4O3S
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| Molecular Weight |
430.848
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| Canonical SMILES |
Fc1ccccc1S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2nccc(=O)n2c1
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| InChI |
InChI=1S/C19H12ClFN4O3S/c20-19-15(24-29(27,28)16-4-2-1-3-14(16)21)9-13(10-23-19)12-5-6-17-22-8-7-18(26)25(17)11-12/h1-11,24H
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| InChIKey |
CMTGOLNCQIYSTQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01045, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT01065, Serine/threonine-protein kinase mTOR