General Information of the Compound
Compound ID
CP0445163
Compound Name
1-(4-chlorophenyl)-3-[3-[6-(cyclopentylamino)pyridin-2-yl]phenyl]urea
    Show/Hide
Structure
Formula
C23H23ClN4O
Molecular Weight
406.917
Canonical SMILES
Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(NC3CCCC3)n2)cc1
    Show/Hide
InChI
InChI=1S/C23H23ClN4O/c24-17-11-13-19(14-12-17)26-23(29)27-20-8-3-5-16(15-20)21-9-4-10-22(28-21)25-18-6-1-2-7-18/h3-5,8-15,18H,1-2,6-7H2,(H,25,28)(H2,26,27,29)
    Show/Hide
InChIKey
GAHMZSAIQOMSRU-UHFFFAOYSA-N
Physicochemical Property
logP
6.4005
Rotatable Bonds
5
Heavy Atom Count
29
Polar Areas
66.05
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 118716108
ChEMBL ID
CHEMBL3341872
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000076 CHO/Galpha16 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 501 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000076 CHO/Galpha16 Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS