General Information of the Compound
Compound ID
CP0445074
Compound Name
4-(3-(4-(N-methylacetamido)phenyl)pentan-3-yl)phenyl azepane-1-carboxylate
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Structure
Formula
C27H36N2O3
Molecular Weight
436.596
Canonical SMILES
CCC(CC)(c1ccc(OC(=O)N2CCCCCC2)cc1)c1ccc(cc1)N(C)C(C)=O
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InChI
InChI=1S/C27H36N2O3/c1-5-27(6-2,22-11-15-24(16-12-22)28(4)21(3)30)23-13-17-25(18-14-23)32-26(31)29-19-9-7-8-10-20-29/h11-18H,5-10,19-20H2,1-4H3
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InChIKey
QJWUDJSBTFQNDT-UHFFFAOYSA-N
Physicochemical Property
logP
6.1502
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
49.85
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44441793
ChEMBL ID
CHEMBL251507
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01430, 3-oxo-5-alpha-steroid 4-dehydrogenase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 = 4700 nM
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