General Information of the Compound
Compound ID
CP0444330
Compound Name
3-(4-(benzyloxy)-3-bromophenyl)-5,7-dichloro-3-methylquinoline-2,4(1H,3H)-dione
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Structure
Formula
C23H16BrCl2NO3
Molecular Weight
505.195
Canonical SMILES
CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1ccc(OCc2ccccc2)c(Br)c1
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InChI
InChI=1S/C23H16BrCl2NO3/c1-23(21(28)20-17(26)10-15(25)11-18(20)27-22(23)29)14-7-8-19(16(24)9-14)30-12-13-5-3-2-4-6-13/h2-11H,12H2,1H3,(H,27,29)
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InChIKey
CFFNCYWPIHCZQR-UHFFFAOYSA-N
Physicochemical Property
logP
6.4276
Rotatable Bonds
4
Heavy Atom Count
30
Polar Areas
55.4
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11504338
SID: 16606222
ChEMBL ID
CHEMBL402292
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS