General Information of the Compound
Compound ID
CP0443074
Compound Name
2-(2-(3-(2-cyclohexylethyl)-1,2,4-oxadiazol-5-yl)-1H-indol-4-yl)-N,N-dimethylethanamine
    Show/Hide
Structure
Formula
C22H30N4O
Molecular Weight
366.509
Canonical SMILES
CN(C)CCc1cccc2[nH]c(cc12)-c1nc(CCC2CCCCC2)no1
    Show/Hide
InChI
InChI=1S/C22H30N4O/c1-26(2)14-13-17-9-6-10-19-18(17)15-20(23-19)22-24-21(25-27-22)12-11-16-7-4-3-5-8-16/h6,9-10,15-16,23H,3-5,7-8,11-14H2,1-2H3
    Show/Hide
InChIKey
GQUAQFCXXCXPMV-UHFFFAOYSA-N
Physicochemical Property
logP
4.8349
Rotatable Bonds
7
Heavy Atom Count
27
Polar Areas
57.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 136043771
ChEMBL ID
CHEMBL210504
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS