General Information of the Compound
Compound ID
CP0441383
Compound Name
1-(Benzenesulfonyl)-5-(piperazin-1-yl-methyl)-1H-indole
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Structure
Formula
C19H21N3O2S
Molecular Weight
355.463
Canonical SMILES
O=S(=O)(c1ccccc1)n1ccc2cc(CN3CCNCC3)ccc12
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InChI
InChI=1S/C19H21N3O2S/c23-25(24,18-4-2-1-3-5-18)22-11-8-17-14-16(6-7-19(17)22)15-21-12-9-20-10-13-21/h1-8,11,14,20H,9-10,12-13,15H2
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InChIKey
XZIRCFVAGCAFDA-UHFFFAOYSA-N
Physicochemical Property
logP
2.2835
Rotatable Bonds
4
Heavy Atom Count
25
Polar Areas
54.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 25024930
ChEMBL ID
CHEMBL1785068
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2.52 nM
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