General Information of the Compound
Compound ID
CP0439912
Compound Name
1-[4-[2-(1H-benzimidazol-2-yl)ethyl]phenyl]-3-(2-methoxy-5-methylphenyl)urea
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Structure
Formula
C24H24N4O2
Molecular Weight
400.482
Canonical SMILES
COc1ccc(C)cc1NC(=O)Nc1ccc(CCc2nc3ccccc3[nH]2)cc1
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InChI
InChI=1S/C24H24N4O2/c1-16-7-13-22(30-2)21(15-16)28-24(29)25-18-11-8-17(9-12-18)10-14-23-26-19-5-3-4-6-20(19)27-23/h3-9,11-13,15H,10,14H2,1-2H3,(H,26,27)(H2,25,28,29)
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InChIKey
SQVZNPUDQJQYQK-UHFFFAOYSA-N
Physicochemical Property
logP
5.30912
Rotatable Bonds
6
Heavy Atom Count
30
Polar Areas
79.04
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46382290
ChEMBL ID
CHEMBL4591596
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01390, BDNF/NT-3 growth factors receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 20000 nM
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