General Information of the Compound
Compound ID
CP0439367
Compound Name
N-[[5-(4-chlorophenyl)-1-cyclohexyl-4-(2,4-dichlorophenyl)imidazol-2-yl]methyl]cyclopentanamine
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Structure
Formula
C27H30Cl3N3
Molecular Weight
502.917
Canonical SMILES
Clc1ccc(cc1)-c1c(nc(CNC2CCCC2)n1C1CCCCC1)-c1ccc(Cl)cc1Cl
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InChI
InChI=1S/C27H30Cl3N3/c28-19-12-10-18(11-13-19)27-26(23-15-14-20(29)16-24(23)30)32-25(17-31-21-6-4-5-7-21)33(27)22-8-2-1-3-9-22/h10-16,21-22,31H,1-9,17H2
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InChIKey
ICFIGBSLHNFWNQ-UHFFFAOYSA-N
Physicochemical Property
logP
8.7147
Rotatable Bonds
6
Heavy Atom Count
33
Polar Areas
29.85
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45271896
ChEMBL ID
CHEMBL551938
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
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