General Information of the Compound
Compound ID
CP0438019
Compound Name
N-[2-(ethylaminomethyl)-3-(2-hydroxy-2-methylpropyl)imidazo[4,5-c]quinolin-4-yl]benzamide
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Structure
Formula
C24H27N5O2
Molecular Weight
417.513
Canonical SMILES
CCNCc1nc2c(c(NC(=O)c3ccccc3)nc3ccccc23)n1CC(C)(C)O
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InChI
InChI=1S/C24H27N5O2/c1-4-25-14-19-27-20-17-12-8-9-13-18(17)26-22(21(20)29(19)15-24(2,3)31)28-23(30)16-10-6-5-7-11-16/h5-13,25,31H,4,14-15H2,1-3H3,(H,26,28,30)
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InChIKey
LCDWPYAKBLLLHS-UHFFFAOYSA-N
Physicochemical Property
logP
3.7172
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
92.07
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56683347
ChEMBL ID
CHEMBL1795690
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02160, Toll-like receptor 7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 21170 nM
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