General Information of the Compound
| Compound ID |
CP0437861
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| Compound Name |
1-(5-chloro-2,4-dimethoxyphenyl)-3-[4-[2-(1-ethylbenzimidazol-2-yl)ethyl]phenyl]urea
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| Structure |
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| Formula |
C26H27ClN4O3
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| Molecular Weight |
478.98
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| Canonical SMILES |
CCn1c(CCc2ccc(NC(=O)Nc3cc(Cl)c(OC)cc3OC)cc2)nc2ccccc12
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| InChI |
InChI=1S/C26H27ClN4O3/c1-4-31-22-8-6-5-7-20(22)29-25(31)14-11-17-9-12-18(13-10-17)28-26(32)30-21-15-19(27)23(33-2)16-24(21)34-3/h5-10,12-13,15-16H,4,11,14H2,1-3H3,(H2,28,30,32)
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| InChIKey |
CIEAJZWSESCRGI-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01390, BDNF/NT-3 growth factors receptor
Protein ID: PT00934, High affinity nerve growth factor receptor