General Information of the Compound
Compound ID
CP0437167
Compound Name
2-(2,6-diethylphenyl)-4-ethoxy-N-ethyl-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine
    Show/Hide
Structure
Formula
C33H38N2O
Molecular Weight
478.68
Canonical SMILES
CCOc1cc(nc2CCCC(N(CC)c3cccc4ccccc34)c12)-c1c(CC)cccc1CC
    Show/Hide
InChI
InChI=1S/C33H38N2O/c1-5-23-15-11-16-24(6-2)32(23)28-22-31(36-8-4)33-27(34-28)19-13-21-30(33)35(7-3)29-20-12-17-25-14-9-10-18-26(25)29/h9-12,14-18,20,22,30H,5-8,13,19,21H2,1-4H3
    Show/Hide
InChIKey
BQMYVJFIUYEZOY-UHFFFAOYSA-N
Physicochemical Property
logP
8.3292
Rotatable Bonds
8
Heavy Atom Count
36
Polar Areas
25.36
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 25191765
SID: 57300377
ChEMBL ID
CHEMBL261276
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02772, C5a anaphylatoxin chemotactic receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 67 nM
   TI
   LI
   LO
   TS